# Selank

A sibling of Semax from the same Russian institute, registered in Russia for anxiety. Elsewhere it is sold as a calming nasal spray that does not sedate. We found no double-blind, placebo-controlled trial.

Also called: TP-7
Source page: https://peplogue.com/peptides/selank/
Reviewed: 2026-10-12. Not medical advice.

## How it works

- Where it acts: Thought to influence GABA signalling and slow the breakdown of enkephalins, the brain's calming peptides.
- What it changes: In animals and small Russian studies, less anxiety without sedation.
- What people notice: Calm without drowsiness is what users report. Strong trial evidence is lacking.

## What the evidence shows

- **Anxiety**: Early. In a 70-person open trial funded by the maker, adding Selank to a benzodiazepine raised the response rate from 23% to 40%, a difference that could be chance.
- **Memory and focus**: Lab only. No controlled trials found.

## Side effects and risks

- unknown: No systematic safety data. FDA says it lacks key information on safety in people.

Who should avoid it: Treat it as untested.

## How it has been given in studies

The trial used 2.7 mg a day for two to three weeks. In Russia it is sold as nose drops.

## Legal status

- United States: undefined. Its compounding nomination was withdrawn, and it is not on the list pharmacies may compound from.
- European Union: undefined
- Spain: undefined. No selank medicine in CIMA. Not authorised in Spain and not lawful to sell to the public.
- Germany: undefined. Not approved in Germany. Selling it as a medicine without approval is a crime (AMG § 21, § 96); sold online only as 'research' products.
- France: undefined. No French authorisation found. Not named by ANSM, but its Jul 2026 alert says peptides bought outside the official circuit are illegal.
- Italy: undefined. No Italian authorisation found. Not lawful to sell to the public as a medicine. Research-grade vials online are unverified products.
- Netherlands: undefined. No Dutch marketing authorisation found. Selling it as a medicine without one is illegal per IGJ, even if labelled 'research use'.
- United Kingdom: undefined
- Canada: undefined
- Australia: undefined

## Questions people ask

**Does Selank work for anxiety?**

The evidence is weak. In a 70-person open trial funded by the maker, adding Selank to a benzodiazepine raised the response rate from 23% to 40%, a difference that could be chance.

**What is the difference between Selank and Semax?**

Selank is a sibling of Semax from the same Russian institute. Selank is registered in Russia for anxiety and is sold elsewhere as a calming nasal spray that does not sedate.

**What are the side effects of Selank?**

There are no systematic safety data, and FDA says it lacks key information on safety in people. Users report tiredness and a mild effect that fades with use.

**Is Selank legal in the US?**

Its compounding nomination was withdrawn, and it is not on the list pharmacies may compound from. An advocacy group found it in declared US peptide imports in early 2026.

## Sources

- Medvedev et al. 2015: Selank added to phenazepam (Korsakov Journal): https://www.mediasphera.ru/issues/zhurnal-nevrologii-i-psikhiatrii-im-s-s-korsakova/2015/6/391997-72982015065
- Partnership for Safe Medicines: peptide import records (9 Jun 2026): https://www.safemedicines.org/2026/06/fishy-peptide-freight.html
- FDA: bulk substances that may present significant safety risks: https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks